Sam Mangwana (born February 21, 1945), is a Congolese soukous vocalist.

Sam Mangwana was born in Kinshasa, Democratic Republic of Congo to Angolan parents. Mangwana grew up listening to foreign musicians touring Kinshasa, especially those from Cuba, who greatly influenced the development of Congolese music. Sam belonged to many bands throughout his career, beginning with Tabu Ley Rochereau and Dr. Nico's band African Fiesta in 1962.