Saturation
Richard O Lyrics


We have lyrics for 'Saturation' by these artists:


Anxiety Whispers When the gun in my mouth Speaks to me, my gun…
Die Cheerleader Saturation I've always wondered why you can't feel Did you h…
ero808 You're a hell of a drug I can't get enough of…
FOAD Sukoshi zutsu karamari kagami ni utsutta Kubisuji to fure ra…
Grey Daze Let me tell you 'bout myself Some say I've got a…
Jethro Tull They left me, leaving my house on fire, me running…
John Frusciante I feel that wheels are turning 'round Replay We made you wha…
Lavender Boy You've got me thinking bout the time when I first…
Linkin Park Let me tell you 'bout myself Some say I've got a…
Pestilence Flooded with the energy of a thousand souls Chaos merging wi…
SATCF Saturation You lost your attention Repeatedly fails "I won't…
The Superjesus Colour, in the shade of winters' tide. I'm not waiting. Divi…
Tourbillon Know what? 見えてるcry? 溢れてる この世界にある 悲しみはdon't small 刻まれているこの痕は …
Valis Ablaze We've been blind so long These colours just seem so wrong An…
Vampire Rodents We're so very smart We need you to know it If we…
yusukeP feat. Hatsune Miku 少しずつ絡まり鏡に映った 首筋と触れられる唇にただ 溺れてゆく 髪を撫でるその手重ねる指先 重なった瞳に深く魅せられてく…



Zoot Woman What am I doing, what will I see An opportunity that…


The lyrics are frequently found in the comments by searching or by filtering for lyric videos
Genre not found
Artist not found
Album not found
Song not found
Most interesting comments from YouTube:

Seitan Beats Your Meat

Great interview, as usual 😊

While I understand his arguments, I feel there are flaws in some studies such as: in what world is 40% fat considered “high fat”? That’s less than the SAD

Also, how would he explain fruitatarians not being fat (most seem underweight, actually)? Or the Mastering Diabetes success rate?

Another issue: in the absence of glucose in the diet (aka “carnivore”), meat proteins can be turned into glucose and if eaten in excess, stored as fat, even more so if salt is added (as referenced in the interview)

I see some holes in his ideas, is all I’m saying



Peter Faber

First I have to say: Great that you interviewed someone that's not seeing things the same as you do. Also great that he tries really hard to not be too hard on you. :)

What becomes clear in this conversation is that no ingredient has a single effect all on its own. The effects of Saturated fat and fructose depend a lot on eachother's presence in the diet. On top of that leptin resistance seems to make things worse. Then additionally, the delayed appetite increasing effect of fructose (it takes time for leptin resistance to develop), is another factor that plays into the total effect.

Also protein as a percentage of calories seems to be another factor. Richard focuses more on the uric acid effect, but perhaps the increased metabolic rate from a higher percentage of protein is another factor that changes outcome.

Then I wonder if there may be an elephant in the room that additionally affects the total effect of the various factors. And that is intermittent fasting. The amount of time you spend in the fed state vs the fasted state. In the fasted state, you'll burn up liver fat. The more time you spend in the fasted state, the more time you are burning up fat that was deposited in the fed state. The ratio may be another factor that affects the amount of fat in the liver.

Lots os variables that make human outcome date really difficult to interprete. Like Richard indicated, most people that are in studies are on high fructose diets to begin with. This is especially true when studying people with existing metabolic disease. It would be interesting if a study could be done on people that have been at least a couple of years on a carnivore diet.

Are your views more nuanced Simon, now that you learned all these new things and perhaps appreciate the complexity of it all a bit better?



Reiner Schafer

@Panes My latest lipid panel results (June 2022):

LDLc: 4.0 mmol/L, 154.68 mg/dL
HDLc: 1.49 mmol/L, 57.62 mg/dL
trigs: .59 mmol/L, 52.26 mg/dL
Non HDL: 4.27 mmol/L, 165.12 mg/dL
Total cholesterol: 5.76 mmol/L, 222.74 mg/dL
chol/HDL risk ratio: 3.87 (ref: <4.9)

So my LDLc is very close to the bottom of the U-shaped curve for all cause mortality. My trig/HDL ratio is a respectable .91 (52.26/57.62)

I'm quite happy with these numbers and they are certainly better than before I was low carb, when ate low fat and even much better from when I ate a low fat vegetarian diet. At that time my LDLc was much lower but nowhere near the bottom of the all cause mortality curve so I'm glad its come up, my HDL was quite low and my trigs were quite high.

hsCRP is also quite low (last test was .6 mg/L)



MAX HARRIS

You have made the mistake that many researchers make in not defining your terms. What do you call high fat? Sobrecases et al. (2010) did the same. Those diets were around 55% carbohydrates, 15 % protein and fat 30%. Then some fat or sucrose or both was added and so the ratios of macronutrients shifted a bit. In the presence of lots of carbohydrate, saturated fat and saturated fat with extra sucrose produces those results but none of these were high fat diets by the definition of a well-formulated ketogenic diet. In the presence of a low carbohydrate (<120g/day ) those effects are not observed. In a diet with <50g/day of carbohydrates it is definitely not observed.All Sobrecases et al. shows is that in the context of a high carbohydrate diet of around 55% of energy from CHO, additional fat and sucrose produce increases in intrahepatocellular lipid. That has nothing to do with what happens in a high fat diet.

AT 33:48 you are talking about adherence and that diets were not adhered to in the long run The paper you have in the screen shot says there were long-lasting, favorable effects for the Mediterranean diet and the low-carb diet, despite a partial regain of weight. The regression is not the fault of the diet; it is to do with not doing the diet in the post intervention period. Show me a diet that works when participants don't do the diet.

AT 47:46 there is discussion of how saturated fat is the worst kind of fat. The paper cited is Luukkonen et al. (2018), in which they overfeed three groups for three weeks. The group are receiving around 30% more food than they need. The group receiving mostly saturated fat as the extra energy intake had the worst outcomes. However, we do not know what the diets of the participants were like; it is likely to be a diet consisting of around 45-55% carbohydrate. Again, this study does not tell you about saturated fats effects, other than in the context of the typical diet, i.e., a diet that consists of 45-55% carbohydrates. In the context of a diet very low in carbohydrates these results are not produced.

Viewers should read for themselves; if possible read the whole article, not just an abstract; and should not just accept accept your interpretations of the research.


Luukkonen, PK, Sädevirta, S, Zhou, Y, Kayser, B, Ali, A, Ahonen, L, … Yki-Järvinen, H 2018, ‘Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars’, Diabetes Care, vol. 41, no. 8, pp. 1732–1739.

Schwarzfuchs, D, Golan, R & Shai, I 2012, ‘Four-Year Follow-up after Two-Year Dietary Interventions’, The New England Journal of Medicine, vol. 367, no. 14, pp. 1373–1374.


Sobrecases, H, Lê, K-A, Bortolotti, M, Schneiter, P, Ith, M, Kreis, R, … Tappy, L 2010, ‘Effects of short-term overfeeding with fructose, fat and fructose plus fat on plasma and hepatic lipids in healthy men’, Diabetes & Metabolism, vol. 36, no. 3, pp. 244–246.



All comments from YouTube:

D. Staal

What a great podcast. Informative, and interesting. And Richard has the hallmark of a real scientist when he a couple of times says: "I don't know " or "I'm not certain". You just cannot know it all, and instead of trying to explain away, he just says it as it is.

Gerritjan Boeve

Great you have R. Johnson on the podcast! Read his book, and found it one of the most intriguing perspectives on 'why we get fat'. Makes a lot of sense in the evolutionary context, as we have to fatten up for winter, so we don't die of starvation. Great podcast, I find myself tuning in regularly.

Gerritjan Boeve

@The Proof with Simon Hill That there is alot of nuance to nutrition. I like that R. Johnson looks at the big picture (evolutionary context), and at the mechanisms( ATP depletion at the mitochondria etc.). It is such a compelling theory for the obesity epidemic. Fructose triggers appetite/survival pathways. Caloric surplus does the rest. Not mentioned here, but in his book he also examines how this pathway evolved in apes. Maybe nice for a follow-up podcast? ;D

Also a good discussion on saturated fat, measurability. Good questions.

Jade Webb

Layla

Eugenie Breida

@The Proof with Simon Hill Biggest takeaway: That you made an effort on behalf of those w/normative weight and calorie intake to understand what could trigger negative liver/lipid/insulin/glucose response.

Would much appreciate keeping normies in the picture, along with, where possible, female (pre and post meno) vs male responses - pushing for further breakdowns, as hormones control so very much (think heart disease).

Thank you Simon.

chiyerano

Learned some new things in this interview such as how we can make fructose in the body. Thank you for this interview.

Signorina Bohemia

What a sweet, highly intelligent and open minded man I liked your first interview with him too, such a great interview keep them coming!

Andrew Boren

Outstanding conversation. Thank you Mr Hill and Dr. Johnson!

Bonnie K

My personal experience: I was diagnosed with fatty liver disease 5 years ago. I was shocked because I’m active and thin. I tried to research the best diet to treat this and thought that Keto diet was good for fatty liver (many YouTube videos on this 😅). So I followed a strict low carb, high fat, moderate protein diet for 1 year (chicken, fish, nuts, coconut oil, avocados, ….). My liver went from 16 cm to 19.4cm (per ultrasound) and liver enzymes went up! But, I lost 10 pounds of body weight! Maybe uric acid contributed to this? I have since changed to plant based with low saturated fats, moderate protein, high complex carbs and, thankfully, my liver size has come back to the previous size. This is such a great informative, conversation. Thank you!!

KD

My experience is similar but not liver related . I did high animal fats (ketovore) to tackle insulin resistance and it gave me stones in my kidneys. I had to swap to lower saturated fats, more plants and also less protein. Doing much better now. I thank this podcast chanel for helping me see the common sense

More Comments

More Versions