iii
C.O.A.G. Lyrics

Jump to: Overall Meaning ↴ Line by Line Meaning ↴

Yeah
Uhuwwwuuooo
Uhuwwwuuooo
Swear, no one even listens anymore
We're lying our hearts out on the floor
No one wants to hear me talk about my face
No one wants to even hear my fucking name
Yeah, I don't even practice anymore

I'll freestyle on the mic when i'm bored
Man no one wants to hear us anymore
Man no ones even out here when i'm bored
Man I don't wanna talk anymore
I'm sick and fucking tired on the floor
No more inspiration for my fucking face
Man can't even get my fucking face
I don't even talk anymore
No ones listening when i'm bored
I know you can hear my fucking name
I know you see me every fucking day
Man no one wanna listen anymore
I'm putting my heart on the floor

Man, no one wants to listen anymore
Saying no one wants to listen anymore

Overall Meaning

This song, "III" by C.O.A.G., seems to be about the frustration of feeling ignored and misunderstood in a world that doesn't seem to have time for genuine connection. The repetition of "no one wants to hear me" and "no one wants to listen" highlights the feeling of being overlooked and disregarded. The lyrics suggest that the singer may have once been interested in pursuing a career in music, but has since lost passion, given up, or hit a creative block. They may have even come to resent the whole industry, feeling that it values fame and performance over authenticity and vulnerability. The final repetition of "saying no one wants to listen anymore" is a bleak and heartbreaking acknowledgement of the singer's loneliness.

The overall tone of the song is one of resignation, mixed with some underlying anger and sadness. There is a sense that the singer has given up on trying to connect with others, and is tired of feeling unheard. The use of profanity and the repetition of certain phrases seem to add to this feeling of frustration and despair.

Line by Line Meaning

Yeah
Introducing the beginning of the song

Uhuwwwuuooo
A vocal expression of emotion

Swear, no one even listens anymore
Expressing disillusionment with the lack of attentive audience

We're lying our hearts out on the floor
The performers are emotionally invested and putting their all into their music

No one wants to hear me talk about my face
A personal anecdote that the audience is not interested in

No one wants to even hear my fucking name
Feeling unimportant and disregarded

Yeah, I don't even practice anymore
Losing motivation to perfect their craft

I'll freestyle on the mic when i'm bored
Using improvisation as a filler when lacking inspiration

Man no one wants to hear us anymore
The audience is no longer interested in their music

Man no ones even out here when i'm bored
Feeling ignored and alone

Man I don't wanna talk anymore
Becoming tired of being invalidated

I'm sick and fucking tired on the floor
Physically and emotionally drained from performing

No more inspiration for my fucking face
Lack of motivation and creativity

Man can't even get my fucking face
Feeling unrecognized and unappreciated

I don't even talk anymore
Will not waste breath speaking to an uninterested audience

No ones listening when i'm bored
Feeling unheard during down time

I know you can hear my fucking name
Clinging to the hope of recognition

I know you see me every fucking day
Awareness of being present, but still disregarded

Man no one wanna listen anymore
Emphasizing the lack of attention and interest from the audience

I'm putting my heart on the floor
Giving their all despite not being acknowledged

Man, no one wants to listen anymore
Reiterating the frustration with a lack of attentive listeners

Saying no one wants to listen anymore
Depicting the overall message of the song as being unheard and overlooked

Lyrics © DistroKid
Written by: Camden Dronenburg

Lyrics Licensed & Provided by LyricFind

To comment on or correct specific content, highlight it

TRACKS

No Related Genres

More Genres

No Artists Found

More Artists Load All

No Albums Found

No Tracks Found

PT1M26S

Genre not found

Artist not found

Album not found

Search results not found

Song not found

Comments from YouTube:

Webermt1

4y↑22

I always come back to this one when I start to forget the details every year. Seriously thank you.
Oh and I remember you test Extrensic with PT and Intrinsic with PTT. (My mnemonic for that is you Play Tennis outside, and you Play Table Tennis Inside)

warevany

same here

Bar bi3

Niccceeee.thnk uuu ..😀

Jennifer T

8y↑39

I've seriously been watching cascade videos for the past hour or more without getting it, and this just did it for me in 6mins! BRILLIANT! ty for uploading

Nikki Riddle

8y↑1

This was AWESOME! I've made my own little charts but I really like how this one put everything together without all the clutter. Perfect for my hematology exam tomorrow =)

Jimi J

11y↑4

Where has this been through out all my time in med school?? Thanks Andrew. Great job!

Jennessa Peterson

12y

Great summary of the coag cascade. I love, love, love the way you did it! Thanks so much for sharing.

Faris Ayyoub

13y

You are amazing mate. Amazing. I swear I've looking into figures and charts for days, this is the first time I actually understand the cascade AND memorize it. Thank you!

nomoreDietCoke

12y

AWESOME, thank you! I've been staring at book-diagrams, and after an hour of trying to simplify it, i'm so glad i found this! thanks again!

Rhys Young

13y↑2

This was very helpful! I'm studying medicine at the moment. Exams are two weeks away and this is the first explanation I've seen which makes sense :) Cheers.

Kristin Wilenius

11y

Thank you! This was a really great video about coagulation :)

Chris Behan

11y

Extremely helpful! I just spent the last few hours reading Robbins when I should've just watched this to begin with.

soundsiffy

10y

I'm on week 3 and your video has made the weeks theme just a little bit less stressful. Thanks :)

Amy Elliott

11y

Thank you so much! This is so much easier to remember than the way I was trying. As well thank you for the detail video (part 2) it helps with some of the drugs I was struggling with :)

Student IPAP

11y

This is the Best COAG Review I've ever seen!! Helped SO Much Thank you!!! I was taught in class that Factor VII required Tissue Factor (Factor III) but that's a minor point. Thank you again!!

caramelgal20

12y

Good job! Thanks for sharing. Also its really cool to remember that the factors requiring calcium for activation are also the ones needing Vit K for synthesis. I never saw it that way.

Sarah Mercy

12y

Thank you! I have a nursing final on monday and Coagulation and the cascade will be a large portion of it :)

Mimi Gottfried

6y↑1

I remember watching this video in my 2nd year for my Biochemistry exam and in my 3rd year for my Clinical Biochemistry exam.

Now I'm in my 5th year and I'm watching this video for my Hematology exam. This video is truly a timeless classic haha. Well done.

Yuliya Linhares

12y

Andrew, you rock. I am preparing for my Hematology Boards (6 years after med. school!), and your simple outline really helped me organize the cascade in my brain. Thank you! I wish you an increadible medical career.

dharkoz Jehu

Thanks for the video so easy to remember. It's much better if you used two colors in circles to differentiate it and put a marked legend in the side of what color means what.... also you forget to mention Prekalikrein and HMWK which binds in XII. I'm currently in hematology 201 and this video help me understand better than my instructor did. Thanks a lot!!!

S W

Interesting and really easy to remember like a stroy! :) Thanks a lot!! God Bless your efforts.

Sirxup

8y↑12

Holy Smokes man.... I know you posted this 5 years ago, but I hope you still read these comments! Great great way to memorize this and put the puzzle pieces together thank you for sharing!

Afairus Putri

Its 9 years ago then, so hi doctor?

Victor Peña-Araujo

12y

Great video Andrew, thanks. Since you evidently appreciate elegant simplicity perhaps consider eliminating all the circles (and even the arrows) and around the Calcium-dependent factors simply make an incomplete circle ("C" for Calcium). This minimizes writing time during an exam while yielding the most information. Again, thank you and best of luck.

Rutaba Arif

so helpful that I came back again to revise the coagulation cascade from it after 2 years!

zinydoodles

12y

love it, thanks! very helpful for me. When I first looked at the coag path, I was like WTF...so many random roman numerals! but your chart made it very simplified and give me a good pattern to remember things by :)

Sarah Jo Wolters

12y

Got a b on my homeostasis test all thanks to your awesome diagram! Thank you so much for helping me understand and easily remember (^_^)

Punya Narain

10y

This video has been super helpful in the first 2 years of medical school - and my classmates agree. :) Now I love the coagulation cascade. Thank you!

Thomas Wagoner

11y

Great job of taking something that I've normally seen as somewhat scattered to look at and putting it in a more easy to digest visual. Thanks!

jik

12y

I am a week away from my Board exam, trying to keep it all together, and you just MADE MY DAY! Thanks!! : )

sweetyetunrefined

THANK YOU!!!! You are a God-send. I'm giving my preliminary exam today, and this was so useful.

Sabina Shukurova

Hi! Awesome video thank you for the breakdown!
Just want to add on that factor II, thrombin also activates factor XI, plasma thromboplastin antecedent.

Jordon Brian

Thanks so much for sharing this!
I am a little confused with the Calcium side of things I thought it was used to activate 13a, 1a, 2a and 10a and that 2a, 7a, 9a and 10a required vitamin K.

jiggamaaan

10y

Thanks Andrew... final exam tomorrow... this turned a whole lecture into 10 mins of youtube... appreciated man.

MrAndemob

4y↑1

Nice and easy to remember; almost too easy - good thing there's a sequel too ;-)

Shoaib Safiullah

11y

Good stuff. Thanks Andrew! Just additional points to note... I believe all those that require Ca-2+ also require phospholipids. Also, factor VII combines with factor III (Tissue Factor... which I think is different from Thromboplastin) to make Extrinisic Tenase.

Ousman L Njie

12y

this is just terrific and you are such a genius -:)!!! it sooo much helped me in ma coagulation exams!!

kanyeast //

I still comeback to this and been recommending this to all my friends. So easy thanks

Markéta Tuzová

I use your video every year (when I forget it :D) and I just love it, thanks :-)

Pardhy37

12y

I'm a second yr qualified Doc in UK and this has helped my revision for surgical exams! Thanx :)

Suadz Acri

thankyou so much ANDREW ..this is really amazing and encouraging.....please aploud more videos not only in haematology but also in biochemistry.....

skatesandkicks

9y↑1

Hey Andrew, that was a fantastic little video. Probably the simplest and the best. Clarity is everything. I haven't watched part two yet, so I don't know if you've explained it yet, but you may want to add in that Thromboplastin is comprised of Tissue Factor and phospholipids. I know most text books out there, university lecture notes (non-in depth), and diagrams on the internet substitute thromboplastin with just tissue factor, and this may confuse some people. I look forward to more of your videos :) Thank you.

Himani Patel

Thank you for this!! Hope med school is going/went well for ya!

yunie96

11y

Thank you very much. This is very helpful to me to learn this complicated pathway. Thank you.

Brian M

8y↑1

this was perfect. thank you for sharing

ArlensGuitars

12y

This is ... AWESOME! Thank you sir! Job well done.

Colton B

12y

Great vid! I'm always looking for study tips and ways to reinforce what I've already learned. If I could offer a bit of advise though. If you're going to be a doctor then you really need to work on your penmanship. It's too legible...

Thomas Peck

you drawing did simplify the process for me. thanks!

Sameeh Daraghmeh

Thank you very much!!!! I can only imagine what I would've done without this video 😅

Alex Wilkinson

9y↑2

Thank you for posting this. I may have interpreted the video wrong, but just in case: my A&P book says factor 7, of the extrinsic pathway, is "proconvertin," & "thromboplastin" is factor 9, of the intrinsic pathway. I'm usually oblivious to details like this, but it was amongst my practice questions for a final (to state whether thromboplastin was of the extrinsic, intrinsic, or common pathway,) & I kept getting it wrong after reviewing this. .. :P **Submitted with respect and gratitude**

Adam Heinemann

11y

Just started studying for step 1 and this has made so much more sense than anything my lecturers have given me. Thanks for sharing.

TrishLovesVNV

12y

this was amazing. Thank you!

Clang Odsigue

11y

Thanks much for this! It really helped in my review. God bless you. :)

DrSajo0o

12y

Finaly I can recall it so easily Thank you ^_^

Lili fayazi

10y

Luvd it...absolutely perfect!!

Edu Cyril

12y

First of all, great video. One thing I would like to point out is that VIIa is prevented from catalyzing Xa by TF Pathway Inhibitor. What eventually happens is that VIIa activates IXa which in turn activates Xa, etc. Also, Ia fibrin is the "mesh" and XIIIa is the "seal". Hope that helps...Thanks

mollerie1

10y

This is amazing. Thanks a lot!

Durray

13y

I just want to add my way to remember most of the Intrinsic pathway. The last letter of the number is the first letter of the next number: TwelvE -> EleveN -> NinE + EighT -> Ten then its just 2 -> 1

Mark M

Good explanation. First platelet plug formation will happen at the site of injured endothelial cells- first factor to interact with this plug is factor 12 then coagulation cascade, enzymatic reaction will happen to make fibrin strand

s4027318

13y

thanks for uploading this! it was really helpful!

abolsen

13y

@nystagmus It is! I think Thrombin (IIa) is the only one to catalyze the reactions I refer to though, right? What point in the video are we talking about? I don't differentiate between activated ("a") factors and their not-yet-active starting molecules because it streamlines how the picture is drawn. One of the shortcuts I use is to assume that anyone writing out this diagram is already familiar with the relationships between "pro-" or "-ogen" factors and their final product.

Fariz Dwiky

12y

Hello! Greetings from Indonesia , I'm a med stud in universitas padjadjaran , thanks for uploading this video ! it helps me so much in exam! :D

Angela Ng

10y

This is great and makes it so much more easier to understand. One little thing to add, I've read a lot of different books and sites and factor 2a activates 11 as well. So just another arrow on your diagram and it's perfect !

Magnus Hillman

12y

Excellent stuff!

Mahmudul Hasan

So great ways to remember.... thanks

hhyu520

13y

Great video. Just a note. According to Robbins Pathology, the conversion of Factor I to Ia & 13 to 13a both require Ca2+

Taetaekim

12y

thanks for making this video~ especially for a quick review~~~

Reham

You did great man 👍🏻

Anett

7y↑2

Thank you so much for the help!! Greetings from Hungary! :)

girldetective18

Oh my gosh, you're awesome!

Andrii Furtak

great lesson! thanks!
If i understood properly, then 10a requires 5a to activate 2a.
But you said that 2a also activates 5a, so it looks like activating of 2a needs 5a and activating of 5a needs 2a but their both activated forms are absent until that moment???

victor bruun

8y↑2

+ Андрій Фуртак
2a increases the affinity of 10a to 2a several 100fold, but the process of 10a activating 2a will still occur in the abscense of 5a. It will just be much, much slower. That's why 5 and 8 are called acceleration factors.

mzmusic4life

Such a helpful video! Thanks so much! :)

Brianna Clark

11y

This is so helpful! Thank you!

Xyza

you the real mvp! thanks for this! helped a loooot! 😊

Abby Bunstine

11y

Thanks Andrew!! You are the bomb!!

Sandra Gboneme

You are so amazing!!!

CrashAriMP5N2O

12y

When I was learning this I also had to know the alternate names (i.e. II = prothrombin IIa = thrombin) with that said, thromboplastin is aka Factor III. The thing about coagulation cascade is that while it is simplified to reduce the process by just stating the products (the factor #a) of each step, one shouldn't forget that each product is a catalyst for the conversion of reactant to product of the next step. I also made simplified steps like what you did minus the a's for the reason above.

Jonathan Kurnia Wijaya

Thanks so much! This helped me a lot! :)

Shaikhah H

Thank You! YOU'RE AMAZING👍

Tony Luna

12y

Andrew thank you for the video... I am a pharmacist student and we are going over the hemostatic pathway too. I noticed that you said that Factor 7a activates Factor 10 to become Factor 10a. Well, we were told on class that Factor 7 actually stimulate Factor 9 to become Factor 9a. So just make sure to check that up for future videos. The overall content is very good.

Drdarkwolf1990

12y

Thanks really that did help,after my teacher screwed it all Keep on the good work

Khang Nguyen

Thank you so much for the explaination. It really helpful. Many thanks from VietNam

Asmae LGUENSAT

11y

Thank you, that was helpful !

Learn turkish with Şeyma تعلم التركية مع شيماء

It was very helpful for me , thank you :)

Damjan Krstevski

Shouldn't factor VII be activated by factor V (proaccelerin)?
Btw great video and explanation

Jessica Calleja

11y

postive feedback provided by thrombin amplifies the production of factors 5a, 8a and 11a (not 13a).

B.A

The activation of pFXIII occurs in the final phase of the clotting cascade by the concerted action of thrombin and Ca2+
;http://physrev.physiology.org/content/91/3/931

Accordingly, F13 should be double circled as well
right?!

Thanks Amazing Video, things are easier now

Jacky D

11y

Doesnt thrombin also contribute to the feedback loop for XI?

Martin Janků

My warmest thanks goes to you, friend :)

Wild Hunt

10y

Gonna start studying this next year and now watching this when I can't understand a sh*t scares me a lot

Mes Naya

10y↑2

yep we study it in our first year too :'(

Alexander Strauß

10y↑6

@XxJomanxX
I am in medical school and we do have this in our first year.

Wild Hunt

10y

@XxJomanxX
I study medical laboratory science not medicine

XxJomanxX

10y

If you'er gonna start studying in medical school then don't worry, we only study these stuff in our third year, it's unlikely to encounter this in the first or even the second year.

Rajnikant Wankhede

Very Good! Nicely explained!

Arun Duraiswamy

10y

Can you explain the modulation of the pathway by the heparin-antithrombin complex?

Kelly G

11y

Are you kidding me?! 6:27 mins to explain and my teacher took an hour! Thank you for this sir!

Abdel Koussih

11y

Very good way of remembering the Coag Cascade flow. I will add: II, VII, IX, and X are Vitamin D dependent as mentioned. they are related to the prothrombine time (PT/INR). Abnormal PT/INR is seen in walfarin treatment, liver domage, poor colonization of the guts (hence...new born babies receiving Vit K at birth). Also to reverse PT/INR....FFP (to replace the factors), anf VIT K (walfaring inhibits VIT K).

nonoooooooooo1

12y

Brilliant !

kasho55

Really great stuff

Frankie Dumlao

Appreciate the video. Can only imagine the days before YouTube.

Kami Corbin

You're a life saver

Elli Novatcheva

I love the way you organized this - just one thing...... isn't Prothrombin II and Thrombin IIa? You were saying several times that Fibrin is IIa (and that's just not righ). Actually, Fibrinogen is I.